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Research highlights from the current issue of Science Magazine
19 Dec
Despite pessimistic forecasts, Europe's large carnivores are making a comeback. Chapron et al. report that sustainable populations of brown bear, Eurasian lynx, gray wolf, – [Read More]
19 Dec
The accumulation of laughing gas in the atmosphere isn't a laughing matter: Nitrous oxide (N2O) is a powerful greenhouse gas and a depleter of ozone. The manufacture of nylon – [Read More]
19 Dec
Cancer therapies that target specific genetic mutations driving tumor growth have shown promising results in patients; however, the response is often short-lived because the tumors – [Read More]
19 Dec
During the last interglacial period, Antarctic Bottom Water (AABW) formation slowed markedly. This densest ocean water sinks to the bottom of the sea, and its production helps to flush – [Read More]
19 Dec
For the immune system, balance is key. Immune cells must learn to eliminate invading pathogens but tolerate self. A cell type called regulatory T cells (Tregs) help to maintain – [Read More]
19 Dec
Auroral arcs within the polar cap are a visual marvel, and they may also indicate trapped energetic plasma in Earth's magnetosphere. Fear et al. combined simultaneous observations – [Read More]
19 Dec
The ability to design proteins gives insight into the relation between a protein's fold and its function and also provides a path to custom proteins for bioengineering applications. – [Read More]
19 Dec
Imaging entire human tissues with a light microscope requires stitching 500+ images together — a digitization process largely confined to advanced laboratories. Greenbaum et al. d – [Read More]
19 Dec
Small molecules that change the oligomeric state of proteins by binding to a site distant from the interface are called allosteric. They often act by taking advantage of intrinsic protein – [Read More]
19 Dec
Diffuse intrinsic pontine gliomas (DIPGs) are aggressive brain tumors primarily affecting children. Because the tumors arise in the brainstem, which controls many vital functions, they – [Read More]
19 Dec
Scattered across our genome are endogenous retroviruses (ERVs), ancient “footprints” of previous viral infections. Scientists do not fully understand their functions, but Zeng et al. – [Read More]
19 Dec
Since the advent of ultrashort laser pulses, chemists have sought to steer reaction trajectories in real time by setting particular molecular vibrations in motion. Using this approach, – [Read More]
19 Dec
In order to maximize the activity of precious metals in catalysis, it is important to place the metal on some support with a high surface area (such as a zeolite) and to maintain the – [Read More]
19 Dec
The high activity of precious metals such as platinum for reactions that occur in fuel cells can be enhanced by alloying with metals such as nickel and cobalt to form shaped nanoparticles, – [Read More]
19 Dec
Enzymes accelerate chemical processes by coaxing molecules into just the right reactive states. Fried et al. now elucidate the way the enzyme ketosteroid isomerase pushes its – [Read More]
19 Dec
Although cells in a tissue are genetically identical and appear the same, they often exhibit variability in their patterns of gene expression. Organisms may need this to prepare for – [Read More]
19 Dec
Enzymes are proteins that are the workhorses of the cell. Designing enzymes with new functions that are also manifested in living systems could be extremely valuable in bioengineering – [Read More]
19 Dec
Global climate models (GCMs) provide broad-brushstroke projections of future climate. These projections lack the resolution required to understand and respond to regional changes. “Downscaling” met – [Read More]
19 Dec
Exosomes are tiny vesicles released from cells that carry proteins, lipids, and nucleic acids: cargo that can affect the biology of recipient cells. In a Perspective, Anastasiadou and – [Read More]
19 Dec
In response to microbes, innate immune cells activate the transcription factor NF-κB, resulting in pro-inflammatory cytokine release. Once an infection has been resolved, NF-κB signaling m – [Read More]
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