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Research highlights from the current issue of Science Magazine
24 Apr
It would be great to clean up dust by vaporizing it, but even powerful blasting by an exploding star doesn't seem capable of this. Supernovae produce vast amounts of dust, but it is – [Read More]
24 Apr
Stable isotopes of a molecule can clump together in several combinations, depending on their mass. Even for simple molecules such as O2, which can contain 16O, – [Read More]
24 Apr
As there are so few possibilities for drugs and vaccines that protect against the Ebola virus (EBOV), we need more options. Marzi et al. present initial studies in monkeys – [Read More]
24 Apr
Loss-of-function mutations may only produce a mutant phenotype when both copies of the gene are mutated. Gantz and Bier developed a method they call mutagenic chain reaction (MCR) that – [Read More]
24 Apr
Although chicken soup and plenty of rest get most kids through an influenza virus infection, some require hospitalization. Ciancanelli et al. report on one child who suffered – [Read More]
24 Apr
It is not easy to predict a patient's response to chemotherapy with animal models and cultured cells. The true test of responsiveness requires the evaluation of drug activity within – [Read More]
24 Apr
Protein assembly in vitro is useful for studying small molecules but is problematic for studying the assembly of larger, more complex proteins. Kim et al. analyzed the biogenesis – [Read More]
24 Apr
If left untreated, high blood pressure can lead to abnormally enlarged hearts (a condition called pathological hypertrophy) and heart failure. Inhibitors of protein kinase C (PKC) isoforms – [Read More]
24 Apr
Foam cups, foam pellets, plastic cutlery: All are made of polystyrene, which in turn is made of styrene. The massive manufacturing scale of this commodity chemical places a premium – [Read More]
24 Apr
It is easy to imagine that the relatively small and dense compact elliptical galaxies once had more to them. Especially when massive galactic neighbors are seen nearby that may have – [Read More]
24 Apr
The basis of cellular function is where and when proteins are expressed and in what quantities. Single-molecule fluorescence in situ hybridization (smFISH) experiments quantify the – [Read More]
24 Apr
Self-assembly often occurs when dissimilar molecular fragments are forced together by covalent bonding. Surfactants or block copolymers are two common examples. Huang et al. – [Read More]
24 Apr
A key issue in the economics of science is finding effective mechanisms for innovation. A concern about research grants and other research and development subsidies is that the public – [Read More]
24 Apr
Axons, the long protrusions of nerve cells, are programmed to self-destruct under certain conditions that occur during development, stress, or disease states. Gerdts et al. – [Read More]
24 Apr
The synthesis of proteins from mRNA by the ribosome is highly regulated. But newly synthesized protein chains can still block the ribosome exit tunnel and slow protein synthesis. Goldman – [Read More]
24 Apr
The matrikine acetyl-prolineglycine-proline (N-α-PGP) regulates endothelial permeability in inflammatory disease. Xu et al. probed the loss of barrier function of the endothelium, – [Read More]
24 Apr
Most species of plants and animals live in symbiotic relationships with other organisms. For example, many insects rely on bacteria within their cells—endosymbionts—to supply nutrients, and – [Read More]
24 Apr
The deposition of thin films from multiple materials is essential to a range of materials fabrication processes. Layer-by-layer processes involve the sequential deposition of two or – [Read More]
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