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Moderna takes another expansion step, snapping up Japanese mRNA company

Jan 05, 2023 (thepharmaletter.com) - Taking advantage of the vast cash pile generated by the success of its COVID-19 vaccine Spikevax, US mRNA therapeutics and vaccines specialist Moderna (Nasdaq: MRNA) today announced its first out-right acquisition since its launch in 2020.

Moderna revealed that it has reached an agreement to acquire Tokyo, Japan-based start-up OriCiro Genomics, a pioneer in cell-free DNA synthesis and amplification technologies, for $85 million.

"With this acquisition, we obtain best-in-class tools for cell-free synthesis and amplification of plasmid DNA, a key building block in mRNA manufacturing," said Stéphane Bancel, chief executive of Moderna, adding: "OriCiro's technology strategically complements our manufacturing expertise and further accelerates our research and development engine. We look forward to welcoming the OriCiro team to Moderna."

With a broader objective, Mr Bancel said he wants Moderna to be “the best mRNA platform,” and “we really want to look around the world.”

"Moderna has demonstrated remarkable speed and ability to impact lives through their innovative platform and mRNA therapeutics. I am confident that our technology and talent will be a highly strategic fit with Moderna," said Nasir Kato Bashiruddin, chief executive of OriCiro.

"We are thrilled to join forces with Moderna to realize the full power of OriCiro for the benefit of patients," added Seiji Hirasaki, president and co-founder of OriCiro.

OriCiro's proprietary technologies are positioned to unlock and expedite the possibilities of advanced therapeutics and synthetic biology by providing a powerful tool to be used for research, development and manufacturing of plasmid DNA, the company noted. ...continue reading

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Japan’s World Cup campaign ended in the cruelest possible fashion on June 29, as Gabriel Martinelli scored in the fifth minute of stoppage time to give Brazil a 2-1 victory over the Samurai Blue in their knockout match in Houston. Japan had led in the first half and were still level at 1-1 in the final moments, but Martinelli’s late strike sent Brazil into the Round of 16 and eliminated Japan from the tournament.

Strong earthquakes have continued to shake parts of Japan in recent weeks, with 11 temblors measuring lower 5 or above on the Japanese seismic intensity scale recorded across the country since April 2026.

A Kintetsu Railway train derailed inside Kyoto Station on the morning of June 29, forcing partial suspensions on the Kintetsu Kyoto Line for the rest of the day and causing long delays that hit commuters, students and tourists.

A section of stone wall at Hikone Castle, one of Japan’s few surviving original Edo-period castles and a National Treasure whose main keep remains intact more than 400 years after its construction, collapsed after heavy rain caused by Typhoons No. 7 and No. 8, Hikone city officials said.

Japan advanced to the knockout stage of the World Cup after a 1-1 draw with Sweden on June 25, finishing second in Group F and setting up a Round of 32 clash with Brazil in Houston.

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Tokyo stocks edged higher on June 29 as investors bought back selected shares after a sharp AI-led selloff, but gains were capped by caution over high technology valuations, Middle East tensions and a weakening yen that fell to its lowest level against the dollar since 1986.

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